\documentclass[12pt]{article}
\thispagestyle{empty}
\usepackage{hyperref}
\usepackage{amsmath}
\begin{document}
\huge{
$\langle \left(x-\langle x \rangle\right)^2 \rangle = \langle x^2 \rangle-\langle x \rangle^2$
}
\end{document}